Bayesian Dose-Finding Designs using Pharmacokinetics (PK) for Phase I Clinical Trials

Documentation for package ‘dfpk’ version 3.5.1

dfpk-package	Bayesian Dose-Finding Designs using Pharmacokinetics (PK) for Phase I Clinical Trials.
AUC.estim	Estimation of the area under the curve, AUC.
dfpk	Bayesian Dose-Finding Designs using Pharmacokinetics (PK) for Phase I Clinical Trials.
dose-class	An S4 class to perform parameter estimation at each step during a dose-finding trial.
dosefinding-class	An S4 class to represent a dosefinding results.
dtox	Dose finding method DTOX.
invlogit	Inverse logistic functions.
nextDose	Next dose determination of a phase I clinical trial.
nsim	Simulate a single or n prospective clinical trial(s) using the PK measure in the dose finding designs.
pk.estim	The pharmacokinetic's (PK) measure of exposure.
pkcov	Dose finding method PKCOV.
pkcrm	Dose finding method PKCRM.
pklogit	Dose finding method PKLOGIT.
pkpop	Dose finding method PKPOP.
pktox	Dose finding method PKTOX.
plot-method	The graphical representation of dose escalation for each patient in the trial.
plot-method	The graphical representation of dose-finding results.
plot-method	The graphical representation of the drug's concentration in the plasma at time t after the drug administration.
scen-class	An S4 class to represent a simulated scenarios.
show-method	S4 Methods for Function 'show'
show-methods	S4 Methods for Function 'show'
sim.data	Generate and store PK and toxicity data.
stan_f	The data stan_f includes all the Stan models that dfpk package uses.