Nonlinear Mixed Effects Models in Population PK/PD

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Documentation for package ‘nlmixr2’ version 3.0.2

• DESCRIPTION file.
• Package NEWS.

Help Pages

addCwres	Add CWRES
addNpde	NPDE calculation for nlmixr2
addTable	Add table information to nlmixr2 fit object without tables
bobyqaControl	Control for bobyqa estimation method in nlmixr2
bootplot	Produce delta objective function for boostrap
bootstrapFit	Bootstrap nlmixr2 fit
foceiControl	Control Options for FOCEi
lbfgsb3cControl	Control for lbfgsb3c estimation method in nlmixr2
n1qn1Control	Control for n1qn1 estimation method in nlmixr2
newuoaControl	Control for newuoa estimation method in nlmixr2
nlmControl	nlmixr2 defaults controls for nlm
nlmeControl	Control Values for nlme Fit with extra options for nlmixr
nlminbControl	nlmixr2 nlminb defaults
nlmixr2	nlmixr2 fits population PK and PKPD non-linear mixed effects models.
nlmixr2CheckInstall	Check your nlmixr2 installation for potential issues
nlsControl	nlmixr2 defaults controls for nls
optimControl	nlmixr2 optim defaults
preconditionFit	Linearly re-parameterize the model to be less sensitive to rounding errors
profileFixed	Estimate the objective function values for a model while fixing defined parameter values
profileFixedSingle	Estimate the objective function values for a model while fixing defined parameter values
profileLlp	Profile confidence intervals with log-likelihood profiling
saemControl	Control Options for SAEM
setOfv	Set/get Objective function type for a nlmixr2 object
tableControl	Output table/data.frame options
traceplot	Produce trace-plot for fit if applicable
uobyqaControl	Control for uobyqa estimation method in nlmixr2
vpcCens	VPC based on ui model
vpcCensTad	VPC based on ui model
vpcPlot	VPC based on ui model
vpcPlotTad	VPC based on ui model
vpcSim	VPC simulation